Shanghai Cord Blood Bank

1. What is cord blood?
Cord blood, which comes from placenta and umbilical cord and is thrown away normally. With the recent many years study, that found cord blood contained hematopoietic stem cell and can be used in hematopoietic stem cell transplantation for many diseases. Therefore, cord blood became the most important hematopoietic stem cell source, especially for those without blood relation hematopoietic stem cell source. It is also an important biology source for human beings.

2. What is the purpose of collecting cord blood?
Cord blood hematopoietic stem cell is used for hematologic system diseases and immunodeficiency diseases treatment, including ALL, AML, CLL, CML, ML, AA, SCID, MEDITERANEAN ANEMIA, and MEUROBLASTOMA etc.

3. Can cord blood be preserved?
Yes, it can. Cord blood is preserved in cord blood hematopoietic stem cell bank in where passed test, separate, preparation etc procedure and preserved in -196 °C liquid nitrogen for long time.

4. What is cord blood bank?
Cord blood bank is the shortened form of "cord blood hematopoietic stem cell bank", which is the professional medicine institution of cord blood hematopoietic stem cell collection and preservation for the patients. It is also called "cord blood bank" or "life bank", and included common bank and private preservation bank.

5. Why established cord blood bank?
Cord blood included abounded hematopoietic stem cell that can instead of bone marrow in stem cell transplantation. Cord blood transplantation is used for many kind of serious disease, and has the merit of better curative effect, smaller side affection, and lower curative fees. However, because stem cell transplantation required matched HLA and it is very hard to find matched HLA between two without blood relation people. It is become significant to build the bank with large HLA base. On the other hand, cord blood should be disposed and preserved as soon as possible when baby born, Therefore, to establish cord blood bank can preserve the cord blood hematopoietic stem cell such an important biology source, and reach to goal of derived from human being, and serve to human being, at the same time, cord blood bank satisfy the private preservation requirement that keep for future possible use.

6. Why preserve cord blood for child?
Cord blood hematopoietic stem cell is the individual biology source that is the exclusive chance to preserve in whole life, so cord blood preservation is like preserving another life for baby. Cord blood is used in decades of serious disease treatment now, and is developed for many other disease clinical applications. When private preserved cord blood ready to use, it doesn't have to search matched HLA, cell alive possibility is strong, rejection is gently, transplantation success possibility is higher, and curative fees is relative cheaper. Another reason for preservation is that cord blood can be used for other family member, for the future development, cord blood has exceeding high medicine value. It is the seed of organ clone, the method of organ caducity counteracting, the weapon of capture cancer, and clinical test of nerve spinal cord damnification treatment.
Child is continuum of our life, please cherish life and preserve cord blood for him/her.

7. What is the benefit of preservation?
Cord blood hematopoietic stem cell has following benefits:
Cord blood hematopoietic stem cell has no radiation, medical, poison, pathogen or other pollution.
Cord blood hematopoietic stem cell has stronger proliferation ability than bone marrow.
Cord blood collection is much easier and has no any negative effect to lying-in woman and baby.
Cord blood is preserved in -196 °C liquid nitrogen and took out any time if necessary.
Cord blood transplantation has relative gentler rejection.

8. What is the classification of cord blood bank?
Cord blood bank included common bank and private preservation bank.

9. Is there any other cord blood bank in Shanghai?
Probably, but Shanghai cord blood bank is the exclusive one that granted by Ministry of Health People's Republic of China and have legal cord blood bank license in Shanghai.

10. How long can cord blood be preserved?
According to the existing data, cord blood hematopoietic stem cell has been keeping alive ability under cryopreservation for more than ten years. The history of cord blood preservation is nearly twenty years till now, in theory, it can be preserved for a certain long period time. Hematopoietic stem cell has been preserving for over forty years and general histiocyte has been preserving for more than one hundred years under the agone preservation technology. The update preservation technology used PC control temperature, appended special protection reagent to avoid the cell damage. Shanghai cord blood bank used the world's most advanced preservation technology. From the preservation technology aspect, cord blood hematopoietic stem cell can be preserved in Shanghai bank for long period.

11. What is the possibility usage of cord blood in clinical?
Hematopoietic stem cell transplantation has more than thirty years history, before 1980s', the bone marrow transplantation is the main resource of hematopoietic stem cell transplantation, in 1990s' cord blood became more and more focused and the another important composing of stem cell transplantation except bone marrow and peripheral blood. According Stat, the bone marrow program has around 8,000,000.00 donators all around the world, the use possibility is only 0.1%-0.2%, on the contract, cord blood bank has more than 70,000 units, with several years, the use possibility reached to around 3%.

12. What is the difference between donation and private preservation?
If you want to donate cord blood, the only thing that you have to do is to complete the cord blood donation agreement and answer the health question on the health questionary, other procedure is completed by hospital and cord blood bank. The cord blood bank is the ownership of the cord blood. If you want to preserve for self, first of all you have to sign the cord blood preservation contract with cord blood bank and pay a certain preservation fees. The new baby's cord blood is preserved in private preservation bank; someone who preserved is the ownership of the cord blood. This obligee has the right of transferring the said right or permits other family members and a third party without blood relation to use the cord blood stem cells.

13. When is the best moment to collect cord blood? Is there any negative affection?
The best moment of cord blood collection is when baby born, cord blood ligated and broken. The collection people are professional doctor or nurse, the procedure of collection is no any negative affection to both mother and baby. At the mean time, we are guaranteed that we respect privacy for both mother and baby.
How long does it take to send to cord blood bank? And how to preserve the cord blood before that?
Cord blood is preserved between 4-24°C environment, and cord blood bank will pick up within twenty four hours.

14. How to preserve cord blood in cord blood bank? How to keep the quality?
After cord blood bank received cord blood, staff will check lying-in woman information and put into data base, then cord blood will be separated, test, add anti-frozen reagent, PC control reduce temperature, and finally preserved in -196°C liquid nitrogen in GMP room. Every procedure step has PC bar code monitor and two staff check back in order to ensure the cord blood serial number acoup sur. Every test result has two staff look through to ensure the veracity. Every liquid nitrogen tank has computer monitor system and auto alarm system; also, staff will check and record the nitrogen level everyday. Therefore, cord blood preservation is secure absolutely, when cord blood is ready to use, we also identify the gene to avoid mistake use. Shanghai cord blood bank keep private preservation customers secret for the particularity

15. What is the treatment for private preservation?
Private preservation customers have the ownership of cord blood.
Cord blood bank guarantees the quality of cord blood during preservation period, if the child need to use for transplantation and the cord blood is damaged due to cord blood bank's fault, cord blood bank will make a one-time settlement to customer on the basis 1.2 fold of total amount that customer has turned over.

16. What is the difference between cord blood transplantation and bone marrow?
Cord blood collection has no negative affection to both mother and baby, cord blood transplantation doesn't require total HLA matched, 25% possibility of HLA matched exist between sisters/brothers, possibility of HLA matched between without blood relation people is relative higher, the rejection of transplantation is relative gentler.
Bone marrow hemetopoietic stem cell collection required puncture bone marrow, donator need to stay in hospital for whole day. Transplantation required total HLA matched, and the possibility of HLA matched between without blood relation people is much tiny. The rejection of transplantation is relative stronger, which is the main reason to cause transplantation fail.

17. How to preserve for private?
The consulter may come to Shanghai cord blood bank or call hot-line to consult question.
Before the expected date of childbirth, the customer need sign the contract, pay preservation fees and pick the collection bag.
When lying-in woman is in hospital, she should call cord blood bank and explain the hospital name, the expected date of childbirth, the room number and leave contact number.
Lying-in woman give collection bag to doctor and give notice to cord blood bank when she is ready to labour.
Family member call cord blood bank to pick up when cord blood collection is completed.
Cord blood bank will pick up the cord blood within twenty four hours.
Within sixty days after collection, cord blood bank will send preservation contract and cord blood test result to customer.

18. How to donate cord blood?

The consulter can come to Shanghai cord blood bank or call hot-line to consult question.
Lying-in woman notify to doctor or nurse when she is in appointed hospital and fill in the donate agreement.
Answer the health questionary
Provide the address and contact number (for our interview after birth six months)
Lying-in woman give collection bag to doctor and give notice to cord blood bank when she is ready to labour.
Family member call cord blood bank to pick up when cord blood collection is completed.
Cord blood bank will pick up the cord blood within twenty four hours.